Sign up to receive email updates and be the first to read new reviews!

E-mail address:

News and Updates
 Benefits of Cannabidiol (CBD)
How Does CBD React With Human Receptors?
As outlined in our article on how CBD works, we have established that Cannabidiol does not react with either of the two receptors (CB1 and CB2). However, the question remains ... what kind of reaction takes place with our other receptors?
To answer this, Cannabidiol does not directly react with CB1 or CB2 receptors. However, it acts in the form of an antagonist with respect to the agonists of the receptors. That’s an eye-opener!

To simplify this, the CBD helps the receptors to perform optimal functioning of their actions. This includes aiding the endocannabinoids of your body. 

Effects Of CBD

To ascertain the effects of CBD we should first examine the functioning of CB1 and CB2 with different chemical compounds. But let’s understand the following terms first;

Agonists – These are the chemicals which trigger the receptor to produce a biological response.
Inverse agonists – These are the chemicals which produce the exact opposite effects to those of Agonists.

Antagonists – These are the chemicals which are the absolute opposite of agonists as they prevent or hinder the functions of a receptor.

Now we get to the point. Following are some of CBD’s functions:

  • It significantly increases the density of CB1 and enhances the effects of other cannabinoids. 

  • It works for your brain as a 5-HT1a receptor. This makes it directly responsible for being an antidepressant, and relaxing agent. This makes CBD potentially an analgesic but without any side effects. 

  • It works as an inverse agonist for the CB2 receptors. This helps in making the CB2 more responsive.  

  • It also affects the putative GPR55 receptor as an antagonist. This aspect is still being further researched. 

  • It also has pharmacological effects which helps in easing the pain and preventing seizures. 

Among the functions above, most of these effects have been researched and proven. There is still some doubt on the part of how these effects are occurring and research is in process.  


As opposed to the functionality of cannabinoids, CBD has a very mild direct effect on the receptors. In fact, it has indirect effects and aids with different functions and makes them more effective. 

Having indirect effects, it has been difficult to measure up its actual effectiveness, up till now. However, several positive effects of this unique phytocannabinoid are being researched. Since the endocannabinoid system is connected to the immune system and the nervous system, and CBD helps enhances their functions, this phytocannabinoid may prove to have a greater medical scope. 

click here for the top rated CBD E-liquid
Home | About Us | Terms and Conditions | Privacy Policy | Contact - All Rights Reserved
CBD E-liquid Reviews header
Top Rated CBD E Liquid
Our #1 Recommendation